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Why does Melarsoprol have to be injected in glass syringes?
The Next CEO of Stack OverflowWhy do different pain killers have different effects on people?Why is medicine used to treat symptoms which are our body's way of telling us something is wrong?Why would it be necessary to take a brand name medication if a generic drug is available?Why does overuse of antibiotics cause resistance?Why some people experience no side effects from a drug?Why do some medications have HCl?Why does anybody still prescribe Citalopram with Escitalopram available (apart from price)?Why is it that some medicines “may” cause a side effect?Why are certain drugs prescribed more often to either males or females?What to do if someone mistakenly ingests food contraindicated by medication requirements?
A WHO document, contains the statement
[Melarsoprol i]njections must be performed using glass syringes.
Why is this the case?
medications
asked Mar 24 at 7:04
Barry HarrisonBarry Harrison
1162
add a comment |
A WHO document, contains the statement
[Melarsoprol i]njections must be performed using glass syringes.
Why is this the case?
medications
asked Mar 24 at 7:04
Barry HarrisonBarry Harrison
1162
add a comment |
A WHO document, contains the statement
[Melarsoprol i]njections must be performed using glass syringes.
Why is this the case?
medications
asked Mar 24 at 7:04
Barry HarrisonBarry Harrison
1162
A WHO document, contains the statement
[Melarsoprol i]njections must be performed using glass syringes.
Why is this the case?
medications
medications
asked Mar 24 at 7:04
Barry HarrisonBarry Harrison
1162
asked Mar 24 at 7:04
Barry HarrisonBarry Harrison
1162
asked Mar 24 at 7:04
Barry HarrisonBarry Harrison
1162
asked Mar 24 at 7:04
Barry HarrisonBarry Harrison
1162
asked Mar 24 at 7:04
Barry HarrisonBarry Harrison
1162
1162
add a comment |
add a comment |
1 Answer
1
active
oldest
votes
Since Melarsoprol is insoluble in water, dosage occurs via a 3.6% propylene glycol intravenous injection.
As propylene glycol can dissolve plastic, the drug should preferably be administered using a glass syringe (only if sterilisation is reliable), otherwise inject immediately (but slowly) using a plastic syringe (Source).
Melarsoprol is sometimes colloquially referred to as "arsenic in antifreeze".
edited Mar 24 at 20:19
Chris Rogers
3,279940
answered Mar 24 at 7:19
ayushayush
311
3
Is there any citation that propylene glycol can dissolve in plastic? Can't we buy antifreeze in plastic?
– Barry Harrison
Mar 24 at 7:22
Answers here require supporting references, so @BarryHarrison is correct that you need to supply a citation.
– Carey Gregory♦
Mar 24 at 15:30
@BarryHarrison - There was a source linked but easily missed as it was provided via a superscript number 1. I have edited the answer to make it clearer
– Chris Rogers
Mar 24 at 20:21
@ChrisRogers Thanks for the edit. I did see that source. I am hoping the answer can be improved by a reference for "arsenic in antifreeze" as well as "propylene glycol can dissolve plastic". I plan on accepting this answer after these edits are made.
– Barry Harrison
Mar 28 at 5:23
@BarryHarrison - Like I said, there is a citation for disovjng plastic. I can see your point on the arsenic in antifreeze. A quick Google search on that gives doi.org/10.1016/j.pt.2018.04.002 which mentions the colloquialism.
– Chris Rogers
Mar 28 at 8:28
|
show 6 more comments
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1 Answer
1
active
oldest
votes
1 Answer
1
active
oldest
votes
active
oldest
votes
active
oldest
votes
Since Melarsoprol is insoluble in water, dosage occurs via a 3.6% propylene glycol intravenous injection.
As propylene glycol can dissolve plastic, the drug should preferably be administered using a glass syringe (only if sterilisation is reliable), otherwise inject immediately (but slowly) using a plastic syringe (Source).
Melarsoprol is sometimes colloquially referred to as "arsenic in antifreeze".
edited Mar 24 at 20:19
Chris Rogers
3,279940
answered Mar 24 at 7:19
ayushayush
311
3
Is there any citation that propylene glycol can dissolve in plastic? Can't we buy antifreeze in plastic?
– Barry Harrison
Mar 24 at 7:22
Answers here require supporting references, so @BarryHarrison is correct that you need to supply a citation.
– Carey Gregory♦
Mar 24 at 15:30
@BarryHarrison - There was a source linked but easily missed as it was provided via a superscript number 1. I have edited the answer to make it clearer
– Chris Rogers
Mar 24 at 20:21
@ChrisRogers Thanks for the edit. I did see that source. I am hoping the answer can be improved by a reference for "arsenic in antifreeze" as well as "propylene glycol can dissolve plastic". I plan on accepting this answer after these edits are made.
– Barry Harrison
Mar 28 at 5:23
@BarryHarrison - Like I said, there is a citation for disovjng plastic. I can see your point on the arsenic in antifreeze. A quick Google search on that gives doi.org/10.1016/j.pt.2018.04.002 which mentions the colloquialism.
– Chris Rogers
Mar 28 at 8:28
|
show 6 more comments
Since Melarsoprol is insoluble in water, dosage occurs via a 3.6% propylene glycol intravenous injection.
As propylene glycol can dissolve plastic, the drug should preferably be administered using a glass syringe (only if sterilisation is reliable), otherwise inject immediately (but slowly) using a plastic syringe (Source).
Melarsoprol is sometimes colloquially referred to as "arsenic in antifreeze".
edited Mar 24 at 20:19
Chris Rogers
3,279940
answered Mar 24 at 7:19
ayushayush
311
3
Is there any citation that propylene glycol can dissolve in plastic? Can't we buy antifreeze in plastic?
– Barry Harrison
Mar 24 at 7:22
Answers here require supporting references, so @BarryHarrison is correct that you need to supply a citation.
– Carey Gregory♦
Mar 24 at 15:30
@BarryHarrison - There was a source linked but easily missed as it was provided via a superscript number 1. I have edited the answer to make it clearer
– Chris Rogers
Mar 24 at 20:21
@ChrisRogers Thanks for the edit. I did see that source. I am hoping the answer can be improved by a reference for "arsenic in antifreeze" as well as "propylene glycol can dissolve plastic". I plan on accepting this answer after these edits are made.
– Barry Harrison
Mar 28 at 5:23
@BarryHarrison - Like I said, there is a citation for disovjng plastic. I can see your point on the arsenic in antifreeze. A quick Google search on that gives doi.org/10.1016/j.pt.2018.04.002 which mentions the colloquialism.
– Chris Rogers
Mar 28 at 8:28
|
show 6 more comments
Since Melarsoprol is insoluble in water, dosage occurs via a 3.6% propylene glycol intravenous injection.
As propylene glycol can dissolve plastic, the drug should preferably be administered using a glass syringe (only if sterilisation is reliable), otherwise inject immediately (but slowly) using a plastic syringe (Source).
Melarsoprol is sometimes colloquially referred to as "arsenic in antifreeze".
edited Mar 24 at 20:19
Chris Rogers
3,279940
answered Mar 24 at 7:19
ayushayush
311
Since Melarsoprol is insoluble in water, dosage occurs via a 3.6% propylene glycol intravenous injection.
As propylene glycol can dissolve plastic, the drug should preferably be administered using a glass syringe (only if sterilisation is reliable), otherwise inject immediately (but slowly) using a plastic syringe (Source).
Melarsoprol is sometimes colloquially referred to as "arsenic in antifreeze".
edited Mar 24 at 20:19
Chris Rogers
3,279940
answered Mar 24 at 7:19
ayushayush
311
edited Mar 24 at 20:19
Chris Rogers
3,279940
edited Mar 24 at 20:19
Chris Rogers
3,279940
edited Mar 24 at 20:19
Chris Rogers
3,279940
3,279940
answered Mar 24 at 7:19
ayushayush
311
answered Mar 24 at 7:19
ayushayush
311
answered Mar 24 at 7:19
ayushayush
311
311
3
Is there any citation that propylene glycol can dissolve in plastic? Can't we buy antifreeze in plastic?
– Barry Harrison
Mar 24 at 7:22
Answers here require supporting references, so @BarryHarrison is correct that you need to supply a citation.
– Carey Gregory♦
Mar 24 at 15:30
@BarryHarrison - There was a source linked but easily missed as it was provided via a superscript number 1. I have edited the answer to make it clearer
– Chris Rogers
Mar 24 at 20:21
@ChrisRogers Thanks for the edit. I did see that source. I am hoping the answer can be improved by a reference for "arsenic in antifreeze" as well as "propylene glycol can dissolve plastic". I plan on accepting this answer after these edits are made.
– Barry Harrison
Mar 28 at 5:23
@BarryHarrison - Like I said, there is a citation for disovjng plastic. I can see your point on the arsenic in antifreeze. A quick Google search on that gives doi.org/10.1016/j.pt.2018.04.002 which mentions the colloquialism.
– Chris Rogers
Mar 28 at 8:28
|
show 6 more comments
3
Is there any citation that propylene glycol can dissolve in plastic? Can't we buy antifreeze in plastic?
– Barry Harrison
Mar 24 at 7:22
Answers here require supporting references, so @BarryHarrison is correct that you need to supply a citation.
– Carey Gregory♦
Mar 24 at 15:30
@BarryHarrison - There was a source linked but easily missed as it was provided via a superscript number 1. I have edited the answer to make it clearer
– Chris Rogers
Mar 24 at 20:21
@ChrisRogers Thanks for the edit. I did see that source. I am hoping the answer can be improved by a reference for "arsenic in antifreeze" as well as "propylene glycol can dissolve plastic". I plan on accepting this answer after these edits are made.
– Barry Harrison
Mar 28 at 5:23
@BarryHarrison - Like I said, there is a citation for disovjng plastic. I can see your point on the arsenic in antifreeze. A quick Google search on that gives doi.org/10.1016/j.pt.2018.04.002 which mentions the colloquialism.
– Chris Rogers
Mar 28 at 8:28
3
3
Is there any citation that propylene glycol can dissolve in plastic? Can't we buy antifreeze in plastic?
– Barry Harrison
Mar 24 at 7:22
Is there any citation that propylene glycol can dissolve in plastic? Can't we buy antifreeze in plastic?
– Barry Harrison
Mar 24 at 7:22
Answers here require supporting references, so @BarryHarrison is correct that you need to supply a citation.
– Carey Gregory♦
Mar 24 at 15:30
Answers here require supporting references, so @BarryHarrison is correct that you need to supply a citation.
– Carey Gregory♦
Mar 24 at 15:30
@BarryHarrison - There was a source linked but easily missed as it was provided via a superscript number 1. I have edited the answer to make it clearer
– Chris Rogers
Mar 24 at 20:21
@BarryHarrison - There was a source linked but easily missed as it was provided via a superscript number 1. I have edited the answer to make it clearer
– Chris Rogers
Mar 24 at 20:21
@ChrisRogers Thanks for the edit. I did see that source. I am hoping the answer can be improved by a reference for "arsenic in antifreeze" as well as "propylene glycol can dissolve plastic". I plan on accepting this answer after these edits are made.
– Barry Harrison
Mar 28 at 5:23
@ChrisRogers Thanks for the edit. I did see that source. I am hoping the answer can be improved by a reference for "arsenic in antifreeze" as well as "propylene glycol can dissolve plastic". I plan on accepting this answer after these edits are made.
– Barry Harrison
Mar 28 at 5:23
@BarryHarrison - Like I said, there is a citation for disovjng plastic. I can see your point on the arsenic in antifreeze. A quick Google search on that gives doi.org/10.1016/j.pt.2018.04.002 which mentions the colloquialism.
– Chris Rogers
Mar 28 at 8:28
@BarryHarrison - Like I said, there is a citation for disovjng plastic. I can see your point on the arsenic in antifreeze. A quick Google search on that gives doi.org/10.1016/j.pt.2018.04.002 which mentions the colloquialism.
– Chris Rogers
Mar 28 at 8:28
|
show 6 more comments
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